CBD zur Stressbewältigung: ein natürliches Anxiolytikum Cbd-oil.market

CBD for stress management: a natural anxiolytic

Stress is an unavoidable part of life that, if left unaddressed, can have a negative impact on our mental and physical health. Chronic stress leads to a number of health problems, including anxiety/restlessness, depression, headaches, upset stomach, high blood pressure, and a weakened immune system (1). Although there are many pharmaceutical options for dealing with stress, these are often associated with undesirable side effects. In this context, natural alternatives are gaining attention, of which cannabidiol (CBD) represents a promising option.

What is CBD?

CBD, or cannabidiol, is one of over 100 chemical substances known as cannabinoids found in the cannabis plant. Unlike the most well-known cannabinoid THC, CBD does not cause intoxication or euphoria (2). Over the past decade, CBD has gained popularity due to its potential therapeutic properties ranging from pain relief to neuroprotection. Of particular interest is the anti-anxiety effect of CBD, making it a natural alternative for stress relief


How does CBD relieve stress?

The human body has a complex biological system called the endocannabinoid system (ECS), which helps regulate a number of bodily functions, including mood, pain, appetite and sleep. The ECS produces its own cannabinoids, or endocannabinoids, which bind to receptors throughout the body. The molecular structure of CBD is very similar to that of endocannabinoids. This allows CBD to dock on cannabinoid receptors in the ECS and thus develop a number of potential effects there (3).

Research suggests that CBD may help restore balance in the ECS, which is often disrupted by chronic stress (4). It appears to modulate neurotransmitter activity and reduce levels of cortisol, one of the main stress hormones. By reducing the excitability of the brain and calming the nervous system, CBD has strong anti-anxiety and stress-reducing properties.

CBD for anxiety/restlessness

Anxiety disorders are one of the most common mental illnesses that are often triggered and exacerbated by high levels of stress. Pharmaceutical medications for anxiety, although effective, can lead to dependence and changes in brain chemistry when taken long-term (5).

In recent years, CBD has shown promising results in treating anxiety in both animal and human studies. A 2019 randomized, placebo-controlled study found that administering CBD before a public lecture significantly reduced participants' anxiety and discomfort (6).

Numerous reviews of the existing literature also show that CBD has the potential to treat general and social anxiety, obsessive-compulsive disorder, panic disorder, PTSD, etc. with minimal side effects (7,8). CBD oil has also been proven to reduce anxiety in children undergoing medical procedures(9).

CBD to combat everyday stress

While occasional stress is stimulating, chronic everyday stress caused by work, family or health problems can gradually lead to serious consequences if left uncontrolled. Lifestyle or diet changes alone are sometimes not enough to cope with increasing daily stress. More and more research is proving CBD's ability to combat everyday anxiety.

In one study, a daily dose of 300 mg of CBD reduced cognitive impairment and discomfort associated with an anxiety-inducing test (public performance in front of an audience). When combined with stress management techniques, CBD can increase overall effectiveness in combating anxiety(10).

In another pilot, two weeks of CBD administration resulted in significant reductions in self-perceived anxiety, sleep disturbances, and depression in healthcare workers (11). The anxiolytic effect was not accompanied by sedation or side effects.

CBD dosage for stress

CBD is offered in various forms, including oils, tinctures, capsules, supplements, and topicals. Oils placed under the tongue appear to be most effective in managing stress and anxiety. Although research on the optimal dosage of CBD is still ongoing, the following general recommendations apply:

- Mild symptoms: 15-25 mg per day

- Moderate symptoms: 25-50 mg per day

- Severe symptoms: 50-100mg per day

It is best to start with low dosages of 5-10 mg and increase gradually. In addition, it makes sense to consult a doctor knowledgeable about CBD, especially when combining it with other medications (12).

Potential risks of CBD use

Although CBD is generally well tolerated, side effects such as diarrhea, appetite disturbances, fatigue, and interactions with certain medications, including blood thinners, may occur. Topical application minimizes systemic absorption and associated adverse effects. CBD should be avoided during pregnancy and breastfeeding as there is insufficient safety data (13).

Additionally , given the limited government regulation of the CBD market, there are often issues with product quality, including inaccurate labeling and contamination. Choosing reputable brands that provide third-party lab reports can minimize the risks associated with substandard products.

In conclusion, there is increasing clinical evidence supporting the therapeutic potential of CBD as a natural anxiolytic that can help manage stress, anxiety and related health risks. By interacting with the ECS to restore homeostasis, CBD calms the mind and body without altering mental state. Although further large-scale human studies are needed, overall, CBD is a promising option for relieving stress and promoting relaxation naturally. When purchasing quality brands, CBD can be a valuable health supplement in today's stressful world.


  1. Yaribeygi, Habib, et al. "The influence of stress on body function: A review." EXCLI journal 16 (2017): 1057-1072.

  1. Blessing, Esther M., et al. "Cannabidiol as a potential treatment for anxiety disorders." Neurotherapeutics 12.4 (2015): 825-836.

  1. Lee, Martin RD, et al. "A narrative review of the evidence for the use of cannabinoids in chronic pain management." The Clinical journal of pain 37.3 (2021): 207-214.

  1. Shannon, Scott, and Janet Opila-Lehman. "Cannabidiol oil for decreasing addictive use of marijuana: a case report." Integrative Medicine (Encinitas, Calif.) 14.6 (2015): 31-35.

  1. Bandelow, Borwin, et al. "World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety, obsessive-compulsive and post-traumatic stress disorders." The world journal of biological psychiatry 9.4 (2008): 248-312.

  1. Zuardi, Antonio Waldo, et al. "Effects of ipsapirone and cannabidiol on human experimental anxiety." Journal of psychopharmacology 7.1_suppl (1993): 82-88.

  1. Peres, Fernanda Ferreira, et al. "Cannabidiol as a promising strategy to treat and prevent movement disorders?" Frontiers in pharmacology 9 (2018): 482.

  1. Shannon, Scott, Nicole Lewis, Heather Lee, and Shannon Hughes. "Cannabidiol in anxiety and sleep: a large case series." The Permanent Journal 23 (2019).

  1. White, Catherine M. "A review of human studies assessing cannabidiol's (CBD) therapeutic actions and potential." The Journal of Clinical Pharmacology 59.7 (2019): 923-934.

  1. Linares, Irina M., et al. "Cannabidiol presents an inverted U-shaped dose-response curve in a simulated public speaking test." Brazilian Journal of Psychiatry 41.1 (2019): 9-12.

  1. Shannon, Scott, and Kenneth Dumas. "Physicians' perspectives on cannabidiol use." The Permanent Journal 23 (2019).

  1. Esposito, Giuseppe, et al. "Cannabidiol in inflammatory bowel diseases: a brief overview." Phytotherapy Research 27.5 (2013): 633-636.

  1. Crippa, Jose Alexandre, et al. "A critical review of the antipsychotic effects of cannabidiol: 30 years of a translational investigation." Current pharmaceutical design 18.32 (2012): 5131-5140
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